What is hereditary spastic paraplegia?

Hereditary Spastic Paraplegia is not a single disease but a group of genetic disorders in which the main feature is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. Onset can be at any age, from the first year of life to old age, depending on the specific genetic form.

How do members experience hereditary spastic paraplegia?

Top 5 symptoms reported by people with hereditary spastic paraplegia*

*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.

Top treatments taken by people for hereditary spastic paraplegia*

*Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Compare treatments taken by people with hereditary spastic paraplegia*

Treatment
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment

(Mylan-Baclofen)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
hereditary spastic paraplegia (1)
Treatment

(Zanaflex)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
hereditary spastic paraplegia (1)

*Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Who has hereditary spastic paraplegia on PatientsLikeMe?

Age

Age Proportion # of patients
<20 2
20s 14
30s 30
40s 43
50s 58
60s 77
70+ 49

Distribution of sex

Sex

Sex Proportion # of patients
Male 106
Female 170

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What is hereditary spastic paraplegia?

Hereditary Spastic Paraplegia is not a single disease but a group of genetic disorders in which the main feature is progressive spasticity in the lower limbs due to pyramidal tract dysfunction. Onset can be at any age, from the first year of life to old age, depending on the specific genetic form.



Common symptoms reported by people with hereditary spastic paraplegia

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Last updated:



Treatments taken by people for hereditary spastic paraplegia

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Mylan-Baclofen)
Type
Prescription Drug
How many have tried
148
Treatment name(s)

(Zanaflex)
Type
Prescription Drug
How many have tried
39

Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
Last updated:


Compare treatments taken by people with hereditary spastic paraplegia

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Mylan-Baclofen)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Treatment name(s)

(Zanaflex)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with hereditary spastic paraplegia, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
Last updated:



Who has hereditary spastic paraplegia on PatientsLikeMe?

  • 0 new patients joined this month
  • 258 say hereditary spastic paraplegia is their primary condition

Age
Age Proportion # of patients
<20 2
20s 14
30s 30
40s 43
50s 58
60s 77
70+ 49
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 29
20-29 years 13
30-39 years 19
40-49 years 19
50-59 years 14
60-69 years 1
70+ years 0

Distribution of sex

Sex
Sex Proportion # of patients
Male 106
Female 170

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 99
Not Diagnosed 14

These charts show data from hereditary spastic paraplegia patients who have completed their condition history
Last updated: