What is primary lateral sclerosis?

Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases.

How do members experience primary lateral sclerosis?

Top 5 symptoms reported by people with primary lateral sclerosis*

*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.

Top treatments taken by people for primary lateral sclerosis*

*Data from patients with primary lateral sclerosis, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Compare treatments taken by people with primary lateral sclerosis*

Treatment
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment

(Rilutek)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
primary lateral sclerosis (2)
Treatment

(Mylan-Baclofen)
Perceived effectiveness
for primary lateral sclerosis (1 evaluation)
Side effects
Total evaluations
1
Tried for
primary lateral sclerosis (1)

*Data from patients with primary lateral sclerosis, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Who has primary lateral sclerosis on PatientsLikeMe?

Age

Age Proportion # of patients
<20 0
20s 6
30s 16
40s 56
50s 141
60s 244
70+ 375

Distribution of sex

Sex

Sex Proportion # of patients
Male 340
Female 494

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What is primary lateral sclerosis?

Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases.



Common symptoms reported by people with primary lateral sclerosis

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Last updated:



Treatments taken by people for primary lateral sclerosis

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Rilutek)
Type
Prescription Drug
How many have tried
107
Treatment name(s)

(Mylan-Baclofen)
Type
Prescription Drug
How many have tried
451

Data from patients with primary lateral sclerosis, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
Last updated:


Compare treatments taken by people with primary lateral sclerosis

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Rilutek)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Treatment name(s)

(Mylan-Baclofen)
Perceived effectiveness
for primary lateral sclerosis (1 evaluation)
Side effects
Total evaluations
1
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with primary lateral sclerosis, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
Last updated:



Who has primary lateral sclerosis on PatientsLikeMe?

  • 1 new patients joined this month
  • 908 say PLS is their primary condition

Age
Age Proportion # of patients
<20 0
20s 6
30s 16
40s 56
50s 141
60s 244
70+ 375
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 11
20-29 years 18
30-39 years 64
40-49 years 106
50-59 years 135
60-69 years 55
70+ years 8

Distribution of sex

Sex
Sex Proportion # of patients
Male 340
Female 494

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 381
Not Diagnosed 81

These charts show data from PLS patients who have completed their condition history
Last updated: